Whole Person Data to Optimize Health

Delivering the high-resolution data needed to power care for every individual.

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As California’s largest non-profit health data network, we bring together clinical, claims, behavioral health, and social care data to improve the wellbeing of people and communities.

Because every record is a life.
Our network is the backbone of a healthier California.

ORGANIZATIONS

HOSPITALS

HEALTH PLANS

INDIVIDUAL RECORDS

Actionable, Whole Person Care

MX is among the first to bring together social health information exchange (SHIE) with health information exchange (HIE) at scale, bridging the gap between clinical care and the community-based needs that drive 80% of health outcomes.

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Powering a Healthy Future

We’re shaping a future where every Californian receives the high-quality, whole person care they deserve. By incorporating hard-to-reach information like behavioral health and social drivers of health (SDOH) with innovative technology, we align state-level goals with real-world community health.

As a best-in-class, non-profit QHIO and California’s largest source for longitudinal health records, we set the standard for health data transformation—putting people at the center of whole person care and public health.

Counties and Public Health

Support populations of focus. Analytics and social care data to connect residents with services and drive equitable health outcomes.

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Health Plans

Drive higher-quality outcomes. Coordinated, whole person care that treats the individual, not just the data, to navigate the member journey.

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HOSPITALS

Support patient transitions. Real-time data to reduce readmissions and meet DxF requirements so no Californian falls through the cracks.

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IPAs & Medical Groups

Drive performance, manage risk. High-resolution data to coordinate care, close persistent gaps, and improve overall quality scores.

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PROVIDERS

See the full picture. Instant access to health records so you can spend less time searching and more time caring for the person.

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Community-Based Organizations

Advance your mission. A unified view of health and social needs to coordinate the essential services that change lives and communities.

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The MX Solution Suite

MX Notify

Automate hospital event notifications to support care transitions and public health interventions.

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MX Access

Instantly access comprehensive health records to inform clinical decision-making.

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MX Analyze

Leverage reports to identify care gaps and target the right interventions.

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MX ENGAGE

View SDOH, clinical, and behavioral health data and use tools to coordinate whole person care.

Explore MX Engage

News and Insights

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A Snapshot of
Our Network

California Roots.
National Connectivity.

Ready to explore what’s possible with the state’s largest non-profit health data network?

Partner with MX

Manifest MedEx (MX) is California’s largest nonprofit health data network. We connect hospitals, health plans, providers, counties, and community organizations so they can securely share clinical, claims, behavioral health, and social care data in real time as permitted.

A health data utility (HDU) is a not-for-profit organization or state government entity with information exchange at its core and multi-stakeholder governance that, through its mission and function, seeks to meet the comprehensive health data delivery and analytics needs of a state’s public and private sectors. 

This HDU model has been developed and advanced by the Consortium for State and Regional Interoperability, of which MX is a founding member. In practice, this means MX builds shared, foundational infrastructure — identity matching, integration/normalization, a longitudinal clinical and administrative data repository, notification services, and analytics — and deploys that infrastructure across multiple healthcare, payer, and public health use cases. We characterize ourselves as being on an active path toward providing the most aspirational capabilities of a statewide HDU. 

A health information exchange helps different organizations securely share records electronically as permitted, so care teams have a more complete picture of a person’s health history, even if that individual has been seen at multiple facilities or may not be able to fully recount their medical history.

An EHR (electronic health record) is the system a clinic, hospital, or medical group uses to store its own patients’ records. An HIE (health information exchange) connects data between these different EHR systems securely and in compliance with complex regulations.

If two organizations happen to use the same EHR system, they might be able to share records with each other directly. But this only may work between organizations on the same EHR; it doesn’t help when organizations use different systems, which is the more common scenario across a person’s full care journey. 

A health information exchange (HIE) solves that broader gap by connecting many different organizations regardless of which EHR system they use. Manifest MedEx already connects with more than 70 different EHR systems across California, so most organizations can join without building a new custom connection, making participation faster, more affordable, and easier to scale across the network.

Health information exchange in California works through a mix of statewide and regional networks, as well as direct connections between individual organizations. Manifest MedEx is California’s largest statewide HIE network, connecting hospitals, doctors, health plans, and other organizations across every county, while a number of smaller, regional health information exchanges also serve specific areas of the state, some affiliated with MX. These networks help a person’s information move with them as they move between health settings. 

California’s Data Exchange Framework (DxF), established in 2021, now requires many organizations across the state to share health information as well. Organizations often connect with a Qualified Health Information Organization (QHIO), a state-designated intermediary, to help them meet these requirements. Manifest MedEx is California’s largest nonprofit QHIO. MX also connects to national networks, which means we can access and share information even from hospitals that aren’t direct MX participants, helping ensure a more complete picture of a person’s care no matter where they were seen.

Manifest MedEx combines and delivers crucial health and social care information across all 58 counties in California. As the largest nonprofit health data network in California, MX securely exchanges more than 53 million health records, connecting a statewide network of more than 4,000 organizations, including 190+ hospitals, 20+ health plans, and 3,200+ ambulatory providers, along with counties, community-based organizations, and other health and social service agencies.

MX brings together and stewards clinical, claims, behavioral health, and social care data to support whole person care and healthier communities. This includes information such as admissions and discharges, lab results, medications, and social drivers of health, giving care teams a fuller picture of each person’s health, not just what happens inside a hospital or clinic.

By connecting real-time health data across the organizations involved in a person’s care, MX helps providers avoid duplicative tests, close care gaps, coordinate care transitions, and respond quickly to changes in someone’s health, especially when that person has been seen at multiple facilities or by multiple providers. Having that history already available helps ensure care isn’t dependent on a person or their caregivers having to remember it themselves.

No. Manifest MedEx is an independent nonprofit organization, not a government agency, though we work closely with state programs including the California Data Exchange Framework (DxF).

Hospitals, medical groups, health plans, county agencies, community-based organizations, and other health and social service entities across California can participate in MX’s network.

Participation in Manifest MedEx is funded through fees paid by participating organizations, along with grant funding that supports specific initiatives. Fees vary based on organization type and the services used. In general, primary care providers join at no cost.

MX follows strict privacy and security standards, including HIPAA compliance and California-specific data protections, to keep health information safe and shared only between authorized organizations. We do not and will not share data without the explicit permission of our participants and in accordance with California and federal law.

Certain categories of health information receive additional protection under California law. In compliance with Assembly Bill 352 (AB 352), Manifest MedEx does not share medical information related to gender-affirming care, abortion, abortion-related services, or contraception with individuals or entities outside of California. Manifest MedEx also complies with 42 CFR Part 2, the federal law protecting the confidentiality of substance use disorder treatment records. 

Manifest MedEx has also earned HITRUST CSF® Certification every year since 2019, one of healthcare’s most rigorous, independently validated security credentials.

You can request access to your own health information through our Individual Access page. If you’d like to opt out of having your data shared through Manifest MedEx, you can do so on our Opt-Out page.