Data Exchanage Framework (DxF) Resources
Meet AB133 health data sharing requirements and participate in the CA Data Exchange Framework with Manifest MedEx, a DxF Qualified Health Information Organization (QHIO)
Every Californian, no matter where one lives within our state, should be able to walk into a doctor’s office, a county social services agency, or an emergency room, and be assured that health and social services providers can access the information they need to provide safe, effective, whole-person care—while keeping our data private and secure.
The Data Exchange Framework (DxF) is the first-ever required statewide data-sharing agreement of its kind in California, and it is key to achieving the state’s plans for transforming healthcare, expanding coverage, advancing equity, and improving connections between health and social services entities.
The DxF creates an unprecedented opportunity for California’s health and human service providers and entities to securely share and access the information needed to treat all California patients quickly, safely, and equitably.
On August 1, 2025, the Data Exchange Framework transitioned from the California Health and Human Services Agency to the California Department of Health Access and Information (HCAI), which now oversees ongoing implementation. Manifest MedEx is dedicated to advancing interoperability and data sharing across California. As a Qualified Health Information Organization (QHIO), we are committed to supporting all DxF participants — regardless of their location, technical capabilities, or resources —to achieve CalAIM and Data Exchange Framework (DxF) goals
We are honored to have participated in the CalHHS DxF Stakeholder Advisory Group, and to continue to participate on the Implementation Advisory Committee, the Data Sharing Agreement and Policies & Procedures Subcommittee, and the 2024 Standards Committee. We're proud to be one of the first organizations to sign the DSA.
Our goal is to provide updates and resources to help you comply with the requirements under the DxF. It’s important to stay updated as the implementation of the Data Exchange Framework continues.
MX DxF Resources
Manifest MedEx Applauds Governor Newsom for Signing SB 660 to Strengthen California’s Data Exchange Framework
Get Real-Time Health Data and Meet Your Data Sharing Requirements with Manifest MedEx
The Center for Data Insights and Innovation (CDII) has released the Data Exchange Framework (DxF) Participant Directory in the DSA Signing Portal!
“Meet Your DxF Requirements with Manifest MedEx, a designated Qualified Health Information Organization (QHIO)” Webinar Recap
Manifest MedEx’s November Webinar – “Meet Your DxF Requirements with Manifest MedEx, a designated Qualified Health Information Organization (QHIO)”
The Data Exchange Framework: What are Qualified Health Information Organizations (QHIOs)?
Manifest MedEx Designated a Qualified Health Information Organization (QHIO) in the California Health and Human Services Data Exchange Framework
For additional resources on DxF and the CalHHS Data Sharing Agreement, check out the following.
CalHHS Resources
Resources directly from CalHHS to know how and when to meet requirements and available DxF grants.
Education Grant Recipient Resources
Training and materials offered to DxF and DSA signatories.
Have you signed the DSA yet using the online signing portal?
See the full updated list of CalHHS Data Exchange Framework Signatories.